DegronMD

Uniprot ID: Q9NVL8

Source protein: Uncharacterized protein CCDC198

Source gene: CCDC198

Class: DEG_APCC_DBOX_1

Location: 147:155

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5041

ASA_SCORE: 103.5

COIL: 0.3371

CONS_SCORE: 0.8313

DSS_SCORE: 0.4213

HELIX: 0.6411

FCONS_SCORE: 1.176

RIG_SCORE: 0.8085

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.M158T	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	NRQYLHKMQ	DEG_APCC_DBOX_1	0.25
p.M158T	SIDM01605	Non-Small Cell Lung Carcinoma	GDSC	NRQYLHKMQ	DEG_APCC_DBOX_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9NVL8	Uncharacterized protein CCDC198	DEG_APCC_DBOX_1	147:155	NRQYLHKMQ	APC,CDC20,FZR1	0.5041	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons