DegronMD

Uniprot ID: Q9H799

Source protein: Ciliogenesis and planar polarity effector 1

Source gene: CPLANE1

Class: DEG_SCF_FBW7_1

Location: 2021:2028

E3 ligase: FBXW7

DEGRON score: 0.84

ASA_SCORE: 105.0375

COIL: 0.9649

CONS_SCORE: 0.4276

DSS_SCORE: 0.6699

HELIX: 0.0194

FCONS_SCORE: 1.0455

RIG_SCORE: 0.6266

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.N2015S	SIDM01005	Acute Myeloid Leukemia	GDSC	PAPTPQKT	DEG_SCF_FBW7_1	0.1667
p.N2015S	KASUMI-1	haematopoietic_and_lymphoid_tissue	COSMIC	PAPTPQKT	DEG_SCF_FBW7_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9H799	Ciliogenesis and planar polarity effector 1	DEG_SCF_FBW7_1	2021:2028	PAPTPQKT	FBXW7	0.84	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons