DegronMD

Uniprot ID: Q9NRR6

Source protein: Phosphatidylinositol polyphosphate 5-phosphatase type IV

Source gene: INPP5E

Class: DEG_SCF_FBW7_2

Location: 55:61

E3 ligase: FBXW7

DEGRON score: 0.9894

ASA_SCORE: 78.5286

COIL: 0.9563

CONS_SCORE: 0.373

DSS_SCORE: 0.7397

HELIX: 0.0196

FCONS_SCORE: 1.0507

RIG_SCORE: 0.5017

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.I70F	DO27817	MALY	ICGC	PATPSGE	DEG_SCF_FBW7_2	0.0833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9NRR6	Phosphatidylinositol polyphosphate 5-phosphatase type IV	DEG_SCF_FBW7_2	55:61	PATPSGE	FBXW7	0.9894	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons