DegronMD

Uniprot ID: Q7Z5P9

Source protein: Mucin-19

Source gene: MUC19

Class: DEG_SCF_FBW7_1

Location: 464:471

E3 ligase: FBXW7

DEGRON score: 0.9823

ASA_SCORE: 77.6125

COIL: 0.8059

CONS_SCORE: 0.5806

DSS_SCORE: 0.5222

HELIX: 0.0903

FCONS_SCORE: 0.9816

RIG_SCORE: 0.733

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A473E	DO233072	GACA	ICGC	PEATPKYS	DEG_SCF_FBW7_1	0.2778
p.A473E	ACH-000975	Lung Cancer	CCLE	PEATPKYS	DEG_SCF_FBW7_1	0.2778
p.C462F	DO229036	LICA	ICGC	PEATPKYS	DEG_SCF_FBW7_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q7Z5P9	Mucin-19	DEG_SCF_FBW7_1	464:471	PEATPKYS	FBXW7	0.9823	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons