DegronMD

Uniprot ID: P78524

Source protein: DENN domain-containing protein 2B

Source gene: DENND2B

Class: DEG_SCF_FBW7_1

Location: 362:368

E3 ligase: FBXW7

DEGRON score: 0.9549

ASA_SCORE: 76.1857

COIL: 0.9211

CONS_SCORE: 0.3595

DSS_SCORE: 0.8473

HELIX: 0.0144

FCONS_SCORE: 0.9252

RIG_SCORE: 0.457

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T364I	SIDM00690	Head and Neck Carcinoma	GDSC	PGTPGNS	DEG_SCF_FBW7_1	0.8189

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P78524	DENN domain-containing protein 2B	DEG_SCF_FBW7_1	362:368	PGTPGNS	FBXW7	0.9549	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons