DegronMD

Uniprot ID: Q5H9F3

Source protein: BCL-6 corepressor-like protein 1

Source gene: BCORL1

Class: DEG_SCF_FBW7_1

Location: 388:395

E3 ligase: FBXW7

DEGRON score: 0.8818

ASA_SCORE: 89.1375

COIL: 0.9434

CONS_SCORE: 0.3826

DSS_SCORE: 0.5353

HELIX: 0.0149

FCONS_SCORE: 0.9585

RIG_SCORE: 0.6826

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P380L	TCGA-B5-A0K1	UCEC	TCGA	PIFTPAPT	DEG_SCF_FBW7_1	0.1111
p.P380L	DO41839	UCEC	ICGC	PIFTPAPT	DEG_SCF_FBW7_1	0.1111
p.P382H	DO222946	BTCA	ICGC	PIFTPAPT	DEG_SCF_FBW7_1	0.1667
p.M397I	DO228948	LICA	ICGC	PIFTPAPT	DEG_SCF_FBW7_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q5H9F3	BCL-6 corepressor-like protein 1	DEG_SCF_FBW7_1	388:395	PIFTPAPT	FBXW7	0.8818	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons