DegronMD

Uniprot ID: Q9NY74

Source protein: Ewing's tumor-associated antigen 1

Source gene: ETAA1

Class: DEG_SCF_FBW7_1

Location: 13:20

E3 ligase: FBXW7

DEGRON score: 0.5736

ASA_SCORE: 105.95

COIL: 0.8928

CONS_SCORE: 0.2977

DSS_SCORE: 0.728

HELIX: 0.0468

FCONS_SCORE: 0.7114

RIG_SCORE: 0.5799

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P11R	TCGA-23-2645	OV	TCGA	PKKTPHKT	DEG_SCF_FBW7_1	0.2778
p.P11R	DO30890	OV	ICGC	PKKTPHKT	DEG_SCF_FBW7_1	0.2778
p.P17R	DO6988	CLLE	ICGC	PKKTPHKT	DEG_SCF_FBW7_1	0.7512
p.G27V	DO223014	ESCA	ICGC	PKKTPHKT	DEG_SCF_FBW7_1	0.1389
p.E24D	DO229032	LICA	ICGC	PKKTPHKT	DEG_SCF_FBW7_1	0.2222
p.R5M	DO229006	LICA	ICGC	PKKTPHKT	DEG_SCF_FBW7_1	0.1111
p.P13Q	ACH-001577	Leukemia	CCLE	PKKTPHKT	DEG_SCF_FBW7_1	0.7035

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9NY74	Ewing's tumor-associated antigen 1	DEG_SCF_FBW7_1	13:20	PKKTPHKT	FBXW7	0.5736	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons