DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
PLATPSPS
Uniprot ID:
Q9H6K5
Source protein:
Proline-rich protein 36
Source gene:
PRR36
Class:
DEG_SCF_FBW7_1
Location:
303:310
E3 ligase:
FBXW7
DEGRON score:
0.96
ASA_SCORE:
85.1375
COIL:
0.9716
CONS_SCORE:
0
DSS_SCORE:
0.7255
HELIX:
0.0111
FCONS_SCORE:
0
RIG_SCORE:
0.5035
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with PRR36 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PLATPSPS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9H6K5
Proline-rich protein 36
DEG_SCF_FBW7_1
303:310
PLATPSPS
FBXW7
0.96
More...