DegronMD

Uniprot ID: Q9P1Y5

Source protein: Calmodulin-regulated spectrin-associated protein 3

Source gene: CAMSAP3

Class: DEG_SIAH_1

Location: 739:747

E3 ligase: SIAH1,SIAH2,SIAH3

DEGRON score: 0.9257

ASA_SCORE: 84.0556

COIL: 0.9067

CONS_SCORE: 0.4196

DSS_SCORE: 0.7074

HELIX: 0.0592

FCONS_SCORE: 1.0349

RIG_SCORE: 0.6274

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D749N	DO223015	ESCA	ICGC	PPAAWVIPG	DEG_SIAH_1	0.2778
p.A729V	DO219878	SKCA	ICGC	PPAAWVIPG	DEG_SIAH_1	0.0556
p.P730S	DO229456	SKCA	ICGC	PPAAWVIPG	DEG_SIAH_1	0.0833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9P1Y5	Calmodulin-regulated spectrin-associated protein 3	DEG_SIAH_1	739:747	PPAAWVIPG	SIAH1,SIAH2,SIAH3	0.9257	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons