DegronMD

Uniprot ID: Q7Z6P3

Source protein: Ras-related protein Rab-44

Source gene: RAB44

Class: DEG_SCF_FBW7_1

Location: 391:398

E3 ligase: FBXW7

DEGRON score: 0.9961

ASA_SCORE: 93.1375

COIL: 0.9456

CONS_SCORE: 0.4352

DSS_SCORE: 0.6348

HELIX: 0.0205

FCONS_SCORE: 1.9521

RIG_SCORE: 0.611

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.V388L	DO228974	LICA	ICGC	PPPTPRAT	DEG_SCF_FBW7_1	0.25
p.V388L	DO229031	LICA	ICGC	PPPTPRAT	DEG_SCF_FBW7_1	0.25
p.P396L	DO232224	PBCA	ICGC	PPPTPRAT	DEG_SCF_FBW7_1	0.7582
p.H386Y	ACH-000979	Prostate Cancer	CCLE	PPPTPRAT	DEG_SCF_FBW7_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q7Z6P3	Ras-related protein Rab-44	DEG_SCF_FBW7_1	391:398	PPPTPRAT	FBXW7	0.9961	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons