DegronMD - Q7Z6P3(RAB44)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V737A	DO225083	BRCA	ICGC	PTPGKS	DEG_SCF_FBW7_1	734:739	Mutation altering degron motif	0.6936
p.V737M	DO218728	GACA	ICGC	PTPGKS	DEG_SCF_FBW7_1	734:739	Mutation altering degron motif	0.7208
p.V388L	DO228974	LICA	ICGC	PPPTPRAT	DEG_SCF_FBW7_1	391:398	Mutation rewiring degron network	0.25
p.V388L	DO229031	LICA	ICGC	PPPTPRAT	DEG_SCF_FBW7_1	391:398	Mutation rewiring degron network	0.25
p.P396L	DO232224	PBCA	ICGC	PPPTPRAT	DEG_SCF_FBW7_1	391:398	Mutation altering degron motif	0.7582
p.H386Y	ACH-000979	Prostate Cancer	CCLE	PPPTPRAT	DEG_SCF_FBW7_1	391:398	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons