DegronMD

Uniprot ID: Q5T0Z8

Source protein: Uncharacterized protein C6orf132

Source gene: C6orf132

Class: DEG_SCF_FBW7_1

Location: 305:312

E3 ligase: FBXW7

DEGRON score: 0.9982

ASA_SCORE: 102.5

COIL: 0.9726

CONS_SCORE: 0.8009

DSS_SCORE: 0.649

HELIX: 0.012

FCONS_SCORE: 1.0554

RIG_SCORE: 0.6157

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P307Q	DO228952	LICA	ICGC	PPPTPVRT	DEG_SCF_FBW7_1	0.5924
p.P307Q	DO229032	LICA	ICGC	PPPTPVRT	DEG_SCF_FBW7_1	0.5924
p.P307Q	DO229041	LICA	ICGC	PPPTPVRT	DEG_SCF_FBW7_1	0.5924
p.R311M	DO229268	THCA	ICGC	PPPTPVRT	DEG_SCF_FBW7_1	0.7521

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q5T0Z8	Uncharacterized protein C6orf132	DEG_SCF_FBW7_1	305:312	PPPTPVRT	FBXW7	0.9982	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons