DegronMD - Q5T0Z8(C6orf132)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T433N	DO233259	GACA	ICGC	PKSSS	DEG_SPOP_SBC_1	434:438	Mutation rewiring degron network	0.3056
p.R76Q	DO233272	GACA	ICGC	VRPLLTFLP	DEG_APCC_DBOX_1	75:83	Mutation altering degron motif	0.7329
p.T624N	DO228948	LICA	ICGC	PQSTT	DEG_SPOP_SBC_1	620:624	Mutation altering degron motif	0.7055
p.P445T	DO228952	LICA	ICGC	PKSSS	DEG_SPOP_SBC_1	434:438	Mutation rewiring degron network	0.1389
p.P307Q	DO228952	LICA	ICGC	PPPTPVRT	DEG_SCF_FBW7_1	305:312	Mutation altering degron motif	0.5924
p.P307Q	DO229032	LICA	ICGC	PPPTPVRT	DEG_SCF_FBW7_1	305:312	Mutation altering degron motif	0.5924
p.P307Q	DO229041	LICA	ICGC	PPPTPVRT	DEG_SCF_FBW7_1	305:312	Mutation altering degron motif	0.5924
p.T1164K	DO229015	LICA	ICGC	PYTTT	DEG_SPOP_SBC_1	1152:1156	Mutation rewiring degron network	0.1111
p.N1163K	DO229035	LICA	ICGC	PYTTT	DEG_SPOP_SBC_1	1152:1156	Mutation rewiring degron network	0.1389
p.N1163K	DO229008	LICA	ICGC	PYTTT	DEG_SPOP_SBC_1	1152:1156	Mutation rewiring degron network	0.1389
p.P713S	DO50970	LICA	ICGC	PTTTS	DEG_SPOP_SBC_1	699:703	Mutation rewiring degron network	0.0556
p.V75I	DO50970	LICA	ICGC	VRPLLTFLP	DEG_APCC_DBOX_1	75:83	Mutation altering degron motif	0.5965
p.E88V	DO23366	LINC	ICGC	VRPLLTFLP	DEG_APCC_DBOX_1	75:83	Mutation rewiring degron network	0.1944
p.P613H	DO45053	LINC	ICGC	PQSTT	DEG_SPOP_SBC_1	620:624	Mutation rewiring degron network	0.1389
p.L631F	DO230993	LUSC	ICGC	PQSTT	DEG_SPOP_SBC_1	620:624	Mutation rewiring degron network	0.1389
p.L631F	DO230990	LUSC	ICGC	PQSTT	DEG_SPOP_SBC_1	620:624	Mutation rewiring degron network	0.1389
p.L631F	DO231007	LUSC	ICGC	PQSTT	DEG_SPOP_SBC_1	620:624	Mutation rewiring degron network	0.1389
p.S703F	DO222904	MELA	ICGC	PTTTS	DEG_SPOP_SBC_1	699:703	Mutation altering degron motif	0.7982
p.T1166I	DO229459	SKCA	ICGC	PYTTT	DEG_SPOP_SBC_1	1152:1156	Mutation rewiring degron network	0.0556
p.R311M	DO229268	THCA	ICGC	PPPTPVRT	DEG_SCF_FBW7_1	305:312	Mutation altering degron motif	0.7521
p.R311M	DO229268	THCA	ICGC	VRTSS	DEG_SPOP_SBC_1	310:314	Mutation altering degron motif	0.7521
p.R76W	SIDM00216	Colorectal Carcinoma	GDSC	VRPLLTFLP	DEG_APCC_DBOX_1	75:83	Mutation altering degron motif	0.8634
p.R76W	ACH-000989	Colon/Colorectal Cancer	CCLE	VRPLLTFLP	DEG_APCC_DBOX_1	75:83	Mutation altering degron motif	0.8634
p.A67D	SIDM00116	Non-Small Cell Lung Carcinoma	GDSC	VRPLLTFLP	DEG_APCC_DBOX_1	75:83	Mutation rewiring degron network	0.1111
p.S313L	ACH-000993	Endometrial/Uterine Cancer	CCLE	VRTSS	DEG_SPOP_SBC_1	310:314	Mutation altering degron motif	0.7667
p.T431I	ACH-001750	Sarcoma	CCLE	PKSSS	DEG_SPOP_SBC_1	434:438	Mutation rewiring degron network	0.25

DegronMD: protein-targeted degradation, mutation and drug response to degrons

C6orf132

UniProt ID: Q5T0Z8

Entrez ID: 647024

Protein name: Uncharacterized protein C6orf132

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for C6orf132 in