DegronMD

Uniprot ID: Q5T0Z8

Source protein: Uncharacterized protein C6orf132

Source gene: C6orf132

Class: DEG_SPOP_SBC_1

Location: 1152:1156

E3 ligase: SPOP

DEGRON score: 0.9982

ASA_SCORE: 88.16

COIL: 0.934

CONS_SCORE: 0.5996

DSS_SCORE: 0.4436

HELIX: 0.0248

FCONS_SCORE: 0.842

RIG_SCORE: 0.7218

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T1164K	DO229015	LICA	ICGC	PYTTT	DEG_SPOP_SBC_1	0.1111
p.N1163K	DO229035	LICA	ICGC	PYTTT	DEG_SPOP_SBC_1	0.1389
p.N1163K	DO229008	LICA	ICGC	PYTTT	DEG_SPOP_SBC_1	0.1389
p.T1166I	DO229459	SKCA	ICGC	PYTTT	DEG_SPOP_SBC_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q5T0Z8	Uncharacterized protein C6orf132	DEG_SPOP_SBC_1	1152:1156	PYTTT	SPOP	0.9982	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons