DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
PRDWLNMLS
Uniprot ID:
Q6ZVT6
Source protein:
Protein CFAP20DC
Source gene:
CFAP20DC
Class:
DEG_APCC_DBOX_1
Location:
620:628
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9133
ASA_SCORE:
63.9556
COIL:
0.4201
CONS_SCORE:
0.6507
DSS_SCORE:
0.6902
HELIX:
0.5428
FCONS_SCORE:
1.0767
RIG_SCORE:
0.6591
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with CFAP20DC mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PRDWLNMLS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q6ZVT6
Protein CFAP20DC
DEG_APCC_DBOX_1
620:628
PRDWLNMLS
APC,CDC20,FZR1
0.9133
More...