DegronMD

Uniprot ID: A8MQ27

Source protein: E3 ubiquitin-protein ligase NEURL1B

Source gene: NEURL1B

Class: DEG_APCC_DBOX_1

Location: 402:410

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5222

ASA_SCORE: 54.1667

COIL: 0.4329

CONS_SCORE: 0.3645

DSS_SCORE: 0.0867

HELIX: 0.0306

FCONS_SCORE: 0.7468

RIG_SCORE: 0.8772

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A417V	ACH-000982	Colon/Colorectal Cancer	CCLE	PRGRLLCVD	DEG_APCC_DBOX_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
A8MQ27	E3 ubiquitin-protein ligase NEURL1B	DEG_APCC_DBOX_1	402:410	PRGRLLCVD	APC,CDC20,FZR1	0.5222	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons