DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
PRSLLPPVC
Uniprot ID:
Q8IYB0
Source protein:
Putative uncharacterized protein MGC39545
Source gene:
-
Class:
DEG_APCC_DBOX_1
Location:
49:57
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.928
ASA_SCORE:
77.5222
COIL:
0.8037
CONS_SCORE:
1
DSS_SCORE:
0.5444
HELIX:
0.1399
FCONS_SCORE:
1
RIG_SCORE:
0.704
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PRSLLPPVC
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8IYB0
Putative uncharacterized protein MGC39545
DEG_APCC_DBOX_1
49:57
PRSLLPPVC
APC,CDC20,FZR1
0.928
More...