DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
PRTPHPS
Uniprot ID:
Q6ZS17
Source protein:
Rho family-interacting cell polarization regulator 1
Source gene:
RIPOR1
Class:
DEG_SCF_FBW7_1
Location:
726:732
E3 ligase:
FBXW7
DEGRON score:
0.9959
ASA_SCORE:
101.1143
COIL:
0.9664
CONS_SCORE:
0.2801
DSS_SCORE:
0.8001
HELIX:
0.013
FCONS_SCORE:
0.9947
RIG_SCORE:
0.5077
Degron related mutations and impact score
Show
10
25
50
100
entries
Search:
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
p.A730T
HCT-116
large_intestine
COSMIC
PRTPHPS
DEG_SCF_FBW7_1
0.7139
p.S733N
DND-41
haematopoietic_and_lymphoid_tissue
COSMIC
PRTPHPS
DEG_SCF_FBW7_1
0.3056
p.A734T
HCT-116
large_intestine
COSMIC
PRTPHPS
DEG_SCF_FBW7_1
0.2778
p.S739N
DND-41
haematopoietic_and_lymphoid_tissue
COSMIC
PRTPHPS
DEG_SCF_FBW7_1
0.25
p.S737N
DND-41
haematopoietic_and_lymphoid_tissue
COSMIC
PRTPHPS
DEG_SCF_FBW7_1
0.1944
Showing 1 to 5 of 5 entries
Previous
1
Next
Drug responses associated with RIPOR1 mutations
Show
10
25
50
100
entries
Search:
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
No data available in table
Showing 0 to 0 of 0 entries
Previous
Next
All proteins holding degron of PRTPHPS
Show
10
25
50
100
entries
Search:
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q6ZS17
Rho family-interacting cell polarization regulator 1
DEG_SCF_FBW7_1
726:732
PRTPHPS
FBXW7
0.9959
More...
Showing 1 to 1 of 1 entries
Previous
1
Next