DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
PRTPNSS
Uniprot ID:
Q8N3J3
Source protein:
Homologous recombination OB-fold protein
Source gene:
HROB
Class:
DEG_SCF_FBW7_1
Location:
317:323
E3 ligase:
FBXW7
DEGRON score:
0.9974
ASA_SCORE:
104.7429
COIL:
0.9626
CONS_SCORE:
0.3443
DSS_SCORE:
0.692
HELIX:
0.0183
FCONS_SCORE:
1.263
RIG_SCORE:
0.5563
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with HROB mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PRTPNSS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8N3J3
Homologous recombination OB-fold protein
DEG_SCF_FBW7_1
317:323
PRTPNSS
FBXW7
0.9974
More...