DegronMD

Uniprot ID: Q5JXC2

Source protein: Migration and invasion-inhibitory protein

Source gene: MIIP

Class: DEG_SCF_FBW7_1

Location: 52:58

E3 ligase: FBXW7

DEGRON score: 0.9606

ASA_SCORE: 94

COIL: 0.9279

CONS_SCORE: 0.4136

DSS_SCORE: 0.6199

HELIX: 0.0274

FCONS_SCORE: 1.2136

RIG_SCORE: 0.5658

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R68W	TCGA-FI-A2D0	UCEC	TCGA	PSTPETS	DEG_SCF_FBW7_1	0.0556
p.R68W	DO43891	UCEC	ICGC	PSTPETS	DEG_SCF_FBW7_1	0.0556
p.T57M	TCGA-L5-A88Z	ESCA	TCGA	PSTPETS	DEG_SCF_FBW7_1	0.7423
p.C66S	SIDM00377	Other Sarcomas	GDSC	PSTPETS	DEG_SCF_FBW7_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q5JXC2	Migration and invasion-inhibitory protein	DEG_SCF_FBW7_1	52:58	PSTPETS	FBXW7	0.9606	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons