DegronMD

Uniprot ID: Q9C0E4

Source protein: Glutamate receptor-interacting protein 2

Source gene: GRIP2

Class: DEG_SCF_FBW7_2

Location: 837:842

E3 ligase: FBXW7

DEGRON score: 0.9928

ASA_SCORE: 80.4667

COIL: 0.8582

CONS_SCORE: 0.3436

DSS_SCORE: 0.8511

HELIX: 0.0933

FCONS_SCORE: 1.1005

RIG_SCORE: 0.5798

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.K832T	YT	haematopoietic_and_lymphoid_tissue	COSMIC	PTPADE	DEG_SCF_FBW7_2	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9C0E4	Glutamate receptor-interacting protein 2	DEG_SCF_FBW7_2	837:842	PTPADE	FBXW7	0.9928	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons