DegronMD

Uniprot ID: P0C671

Source protein: Protein BNIP5

Source gene: BNIP5

Class: DEG_SCF_FBW7_1

Location: 76:81

E3 ligase: FBXW7

DEGRON score: 0.9655

ASA_SCORE: 98.9

COIL: 0.9235

CONS_SCORE: 0.5864

DSS_SCORE: 0.6868

HELIX: 0.0593

FCONS_SCORE: 0.8061

RIG_SCORE: 0.626

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A75T	SIDM00216	Colorectal Carcinoma	GDSC	PTPEET	DEG_SCF_FBW7_1	0.3056
p.T72I	SIDM01016	T-Lymphoblastic Leukemia	GDSC	PTPEET	DEG_SCF_FBW7_1	0.2222
p.T72I	SIDM01263	T-Lymphoblastic Leukemia	GDSC	PTPEET	DEG_SCF_FBW7_1	0.2222

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P0C671	Protein BNIP5	DEG_SCF_FBW7_1	76:81	PTPEET	FBXW7	0.9655	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons