DegronMD

Uniprot ID: Q9P2P6

Source protein: StAR-related lipid transfer protein 9

Source gene: STARD9

Class: DEG_SCF_FBW7_1

Location: 3322:3327

E3 ligase: FBXW7

DEGRON score: 0.9623

ASA_SCORE: 79.4333

COIL: 0.8143

CONS_SCORE: 0.5193

DSS_SCORE: 0.6584

HELIX: 0.0262

FCONS_SCORE: 0.9295

RIG_SCORE: 0.6264

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.V3328F	TCGA-A2-A25A	BRCA	TCGA	PTPQFS	DEG_SCF_FBW7_1	0.3056
p.V3328F	DO3101	BRCA	ICGC	PTPQFS	DEG_SCF_FBW7_1	0.3056
p.S3334Y	TCGA-B5-A0JY	UCEC	TCGA	PTPQFS	DEG_SCF_FBW7_1	0.1389
p.S3334Y	DO43041	UCEC	ICGC	PTPQFS	DEG_SCF_FBW7_1	0.1389
p.G3330S	DO234182	ESAD	ICGC	PTPQFS	DEG_SCF_FBW7_1	0.25
p.S3318F	DO23735	LUAD	ICGC	PTPQFS	DEG_SCF_FBW7_1	0.2222
p.V3328L	ACH-000582	Skin Cancer	CCLE	PTPQFS	DEG_SCF_FBW7_1	0.3056
p.R3333H	ACH-001142	Non-Cancerous	CCLE	PTPQFS	DEG_SCF_FBW7_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9P2P6	StAR-related lipid transfer protein 9	DEG_SCF_FBW7_1	3322:3327	PTPQFS	FBXW7	0.9623	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons