DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
PTRTPPRE
Uniprot ID:
Q9UF83
Source protein:
Uncharacterized protein DKFZp434B061
Source gene:
-
Class:
DEG_SCF_FBW7_2
Location:
178:185
E3 ligase:
FBXW7
DEGRON score:
0.9498
ASA_SCORE:
113.2875
COIL:
0.974
CONS_SCORE:
0.365
DSS_SCORE:
0.8231
HELIX:
0.0105
FCONS_SCORE:
0.9593
RIG_SCORE:
0.5244
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PTRTPPRE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9UF83
Uncharacterized protein DKFZp434B061
DEG_SCF_FBW7_2
178:185
PTRTPPRE
FBXW7
0.9498
More...
Q9UF83
Uncharacterized protein DKFZp434B061
DEG_SCF_FBW7_2
213:220
PTRTPPRE
FBXW7
0.9343
More...