DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
PTRTPPRE
Uniprot ID:
Q9UF83
Source protein:
Uncharacterized protein DKFZp434B061
Source gene:
-
Class:
DEG_SCF_FBW7_2
Location:
213:220
E3 ligase:
FBXW7
DEGRON score:
0.9343
ASA_SCORE:
113.5875
COIL:
0.9635
CONS_SCORE:
0.3674
DSS_SCORE:
0.9172
HELIX:
0.0225
FCONS_SCORE:
0.9169
RIG_SCORE:
0.5151
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of PTRTPPRE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9UF83
Uncharacterized protein DKFZp434B061
DEG_SCF_FBW7_2
178:185
PTRTPPRE
FBXW7
0.9498
More...
Q9UF83
Uncharacterized protein DKFZp434B061
DEG_SCF_FBW7_2
213:220
PTRTPPRE
FBXW7
0.9343
More...