DegronMD

Uniprot ID: O60229

Source protein: Kalirin

Source gene: KALRN

Class: DEG_APCC_DBOX_1

Location: 2228:2236

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9333

ASA_SCORE: 78.1444

COIL: 0.4432

CONS_SCORE: 0.4946

DSS_SCORE: 0.3174

HELIX: 0.513

FCONS_SCORE: 1.3002

RIG_SCORE: 0.8223

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T2227K	COR-L279	lung	COSMIC	QRDFLNALQ	DEG_APCC_DBOX_1	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O60229	Kalirin	DEG_APCC_DBOX_1	2228:2236	QRDFLNALQ	APC,CDC20,FZR1	0.9333	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons