DegronMD

Uniprot ID: P0C7A2

Source protein: Protein FAM153B

Source gene: FAM153B

Class: DEG_APCC_DBOX_1

Location: 252:260

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9004

ASA_SCORE: 87.5778

COIL: 0.614

CONS_SCORE: 1

DSS_SCORE: 0.6956

HELIX: 0.3503

FCONS_SCORE: 1.1

RIG_SCORE: 0.6849

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.Q252R	CW-2	large_intestine	COSMIC	QRGDLEDLE	DEG_APCC_DBOX_1	0.6218

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P0C7A2	Protein FAM153B	DEG_APCC_DBOX_1	252:260	QRGDLEDLE	APC,CDC20,FZR1	0.9004	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons