DegronMD

Uniprot ID: Q9UKL3

Source protein: CASP8-associated protein 2

Source gene: CASP8AP2

Class: DEG_SCF_SKP2-CKS1_1

Location: 456:463

E3 ligase: SKP2,CSK1

DEGRON score: 0.8413

ASA_SCORE: 126.9625

COIL: 0.753

CONS_SCORE: 0.5002

DSS_SCORE: 0.6278

HELIX: 0.2241

FCONS_SCORE: 0.8717

RIG_SCORE: 0.6919

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Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9UKL3	CASP8-associated protein 2	DEG_SCF_SKP2-CKS1_1	456:463	QWENTPLK	SKP2,CSK1	0.8413	More...

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DegronMD: protein-targeted degradation, mutation and drug response to degrons