DegronMD

Uniprot ID: Q8N4C8

Source protein: Misshapen-like kinase 1

Source gene: MINK1

Class: LIG_APCC_ABBAyCdc20_2

Location: 896:902

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9026

ASA_SCORE: 79.8286

COIL: 0.6241

CONS_SCORE: 0.291

DSS_SCORE: 0.6807

HELIX: 0.246

FCONS_SCORE: 1.0172

RIG_SCORE: 0.7267

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.H900R	DO227648	PACA	ICGC	RNLLHAD	LIG_APCC_ABBAyCdc20_2	0.8244

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8N4C8	Misshapen-like kinase 1	LIG_APCC_ABBAyCdc20_2	896:902	RNLLHAD	APC,CDC20,FZR1	0.9026	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons