DegronMD

Uniprot ID: Q7Z2Z1

Source protein: Treslin

Source gene: TICRR

Class: DEG_APCC_DBOX_1

Location: 1237:1245

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.904

ASA_SCORE: 123.0222

COIL: 0.9247

CONS_SCORE: 0.2798

DSS_SCORE: 0.7366

HELIX: 0.0466

FCONS_SCORE: 0.8002

RIG_SCORE: 0.703

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P1236S	TCGA-BR-4201	STAD	TCGA	RRECLTPIR	DEG_APCC_DBOX_1	0.3056
p.P1236S	DO38707	STAD	ICGC	RRECLTPIR	DEG_APCC_DBOX_1	0.3056
p.P1252Q	TCGA-D3-A3CE	SKCM	TCGA	RRECLTPIR	DEG_APCC_DBOX_1	0.1389
p.P1252Q	DO37405	SKCM	ICGC	RRECLTPIR	DEG_APCC_DBOX_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q7Z2Z1	Treslin	DEG_APCC_DBOX_1	1237:1245	RRECLTPIR	APC,CDC20,FZR1	0.904	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons