DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
RRRKLYELH
Uniprot ID:
Q8IX07
Source protein:
Zinc finger protein ZFPM1
Source gene:
ZFPM1
Class:
DEG_APCC_DBOX_1
Location:
742:750
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9853
ASA_SCORE:
132.1222
COIL:
0.5271
CONS_SCORE:
0.3605
DSS_SCORE:
0.7719
HELIX:
0.4742
FCONS_SCORE:
1.0764
RIG_SCORE:
0.673
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with ZFPM1 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of RRRKLYELH
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8IX07
Zinc finger protein ZFPM1
DEG_APCC_DBOX_1
742:750
RRRKLYELH
APC,CDC20,FZR1
0.9853
More...