DegronMD

Uniprot ID: O14511

Source protein: Pro-neuregulin-2, membrane-bound isoform

Source gene: NRG2

Class: DEG_APCC_DBOX_1

Location: 744:752

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.8081

ASA_SCORE: 102.1333

COIL: 0.6386

CONS_SCORE: 0.4991

DSS_SCORE: 0.6147

HELIX: 0.2574

FCONS_SCORE: 1.0785

RIG_SCORE: 0.734

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.Y755C	DO230311	COCA	ICGC	RRSRLNGLA	DEG_APCC_DBOX_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O14511	Pro-neuregulin-2, membrane-bound isoform	DEG_APCC_DBOX_1	744:752	RRSRLNGLA	APC,CDC20,FZR1	0.8081	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons