DegronMD

Uniprot ID: Q68DE3

Source protein: Basic helix-loop-helix domain-containing protein USF3

Source gene: USF3

Class: DEG_COP1_1

Location: 615:625

E3 ligase: COP1

DEGRON score: 0.9507

ASA_SCORE: 96.4909

COIL: 0.9361

CONS_SCORE: 0.514

DSS_SCORE: 0.5296

HELIX: 0.0176

FCONS_SCORE: 0.8278

RIG_SCORE: 0.689

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.N607S	SIDM00388	B-Cell Non-Hodgkin's Lymphoma	GDSC	SNNSVQNVPTP	DEG_COP1_1	0.1111
p.N607S	MHH-PREB-1	haematopoietic_and_lymphoid_tissue	COSMIC	SNNSVQNVPTP	DEG_COP1_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q68DE3	Basic helix-loop-helix domain-containing protein USF3	DEG_COP1_1	615:625	SNNSVQNVPTP	COP1	0.9507	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons