DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
SRASLTRLK
Uniprot ID:
A8MUU9
Source protein:
Putative uncharacterized protein ENSP00000383309
Source gene:
-
Class:
DEG_APCC_DBOX_1
Location:
174:182
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9454
ASA_SCORE:
105.3667
COIL:
0.9346
CONS_SCORE:
0.4225
DSS_SCORE:
0.767
HELIX:
0.0392
FCONS_SCORE:
1.0904
RIG_SCORE:
0.6597
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of SRASLTRLK
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A8MUU9
Putative uncharacterized protein ENSP00000383309
DEG_APCC_DBOX_1
75:83
SRASLTRLK
APC,CDC20,FZR1
0.9847
More...
A8MUU9
Putative uncharacterized protein ENSP00000383309
DEG_APCC_DBOX_1
174:182
SRASLTRLK
APC,CDC20,FZR1
0.9454
More...