DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
SRASLTRLK
Uniprot ID:
A8MUU9
Source protein:
Putative uncharacterized protein ENSP00000383309
Source gene:
-
Class:
DEG_APCC_DBOX_1
Location:
75:83
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.9847
ASA_SCORE:
102.2778
COIL:
0.8724
CONS_SCORE:
0.4097
DSS_SCORE:
0.6907
HELIX:
0.1059
FCONS_SCORE:
1.1055
RIG_SCORE:
0.6984
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of SRASLTRLK
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
A8MUU9
Putative uncharacterized protein ENSP00000383309
DEG_APCC_DBOX_1
75:83
SRASLTRLK
APC,CDC20,FZR1
0.9847
More...
A8MUU9
Putative uncharacterized protein ENSP00000383309
DEG_APCC_DBOX_1
174:182
SRASLTRLK
APC,CDC20,FZR1
0.9454
More...