DegronMD

Uniprot ID: A6QL64

Source protein: Ankyrin repeat domain-containing protein 36A

Source gene: ANKRD36

Class: DEG_APCC_DBOX_1

Location: 1324:1332

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.8993

ASA_SCORE: 86.1111

COIL: 0.6849

CONS_SCORE: 0.3446

DSS_SCORE: 0.5151

HELIX: 0.2389

FCONS_SCORE: 1.0293

RIG_SCORE: 0.7646

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Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A1326S	ACH-000015	Lung Cancer	CCLE	SRDDLDDII	DEG_APCC_DBOX_1	0.7588

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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
A6QL64	Ankyrin repeat domain-containing protein 36A	DEG_APCC_DBOX_1	1324:1332	SRDDLDDII	APC,CDC20,FZR1	0.8993	More...

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DegronMD: protein-targeted degradation, mutation and drug response to degrons