DegronMD

Uniprot ID: Q6UWL2

Source protein: Sushi domain-containing protein 1

Source gene: SUSD1

Class: DEG_APCC_DBOX_1

Location: 11:19

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.6173

ASA_SCORE: 45.9444

COIL: 0.5688

CONS_SCORE: 0.3903

DSS_SCORE: 0.1399

HELIX: 0.0238

FCONS_SCORE: 1.302

RIG_SCORE: 0.8655

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R12H	ACH-000959	Colon/Colorectal Cancer	CCLE	SRRLLPLLL	DEG_APCC_DBOX_1	0.8244

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q6UWL2	Sushi domain-containing protein 1	DEG_APCC_DBOX_1	11:19	SRRLLPLLL	APC,CDC20,FZR1	0.6173	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons