DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
SSSFHSADVPEA
Uniprot ID:
Q9H6A9
Source protein:
Pecanex-like protein 3
Source gene:
PCNX3
Class:
DEG_COP1_1
Location:
706:717
E3 ligase:
COP1
DEGRON score:
0.9599
ASA_SCORE:
70.0333
COIL:
0.7718
CONS_SCORE:
0.3452
DSS_SCORE:
0.5663
HELIX:
0.1238
FCONS_SCORE:
0.9661
RIG_SCORE:
0.6357
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with PCNX3 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of SSSFHSADVPEA
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9H6A9
Pecanex-like protein 3
DEG_COP1_1
706:717
SSSFHSADVPEA
COP1
0.9599
More...