DegronMD - Q9H6A9(PCNX3)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D1868N	SIDM00770	Small Cell Lung Carcinoma	GDSC	PTPENT	DEG_SCF_FBW7_1	1858:1863	Mutation rewiring degron network	0.1944
p.D1868N	NCI-H1836	lung	COSMIC	PTPENT	DEG_SCF_FBW7_1	1858:1863	Mutation rewiring degron network	0.1944
p.R590T	SIDM00946	T-Lymphoblastic Leukemia	GDSC	PTPPAS	DEG_SCF_FBW7_1	598:603	Mutation rewiring degron network	0.1111
p.D283N	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	SGEPTPQK	DEG_SCF_SKP2-CKS1_1	287:294	Mutation rewiring degron network	0.2222
p.D283N	SIDM00773	Non-Cancerous	GDSC	SGEPTPQK	DEG_SCF_SKP2-CKS1_1	287:294	Mutation rewiring degron network	0.2222
p.D283N	SIDM00721	Small Cell Lung Carcinoma	GDSC	SGEPTPQK	DEG_SCF_SKP2-CKS1_1	287:294	Mutation rewiring degron network	0.2222
p.D283N	SIDM00774	Breast Carcinoma	GDSC	SGEPTPQK	DEG_SCF_SKP2-CKS1_1	287:294	Mutation rewiring degron network	0.2222
p.T291M	SIDM00014	Colorectal Carcinoma	GDSC	SGEPTPQK	DEG_SCF_SKP2-CKS1_1	287:294	Mutation altering degron motif	0.8534
p.T291M	LIM1215	large intestine	COSMIC	SGEPTPQK	DEG_SCF_SKP2-CKS1_1	287:294	Mutation altering degron motif	0.8534
p.P600S	SIDM01003	T-Lymphoblastic Leukemia	GDSC	PTPPAS	DEG_SCF_FBW7_1	598:603	Mutation altering degron motif	0.6752
p.P600S	KE-37	haematopoietic and lymphoid tissue	COSMIC	PTPPAS	DEG_SCF_FBW7_1	598:603	Mutation altering degron motif	0.6752
p.P598L	SIDM00145	T-Lymphoblastic Leukemia	GDSC	PTPPAS	DEG_SCF_FBW7_1	598:603	Mutation altering degron motif	0.6471
p.P598L	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PTPPAS	DEG_SCF_FBW7_1	598:603	Mutation altering degron motif	0.6471
p.S603F	SIDM00145	T-Lymphoblastic Leukemia	GDSC	PTPPAS	DEG_SCF_FBW7_1	598:603	Mutation altering degron motif	0.7982

Kaplan plot for PCNX3 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

PCNX3

UniProt ID: Q9H6A9

Entrez ID: 399909

Protein name: Pecanex-like protein 3 (Pecanex homolog protein 3)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for PCNX3 in