DegronMD

Uniprot ID: Q9C0A1

Source protein: Zinc finger homeobox protein 2

Source gene: ZFHX2

Class: DEG_COP1_1

Location: 1919:1927

E3 ligase: COP1

DEGRON score: 0.994

ASA_SCORE: 78.0222

COIL: 0.9588

CONS_SCORE: 0.3446

DSS_SCORE: 0.6493

HELIX: 0.0141

FCONS_SCORE: 0.9097

RIG_SCORE: 0.578

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P1937H	TCGA-EY-A5W2	UCEC	TCGA	STPGGVPSP	DEG_COP1_1	0.0556
p.P1937H	DO48177	UCEC	ICGC	STPGGVPSP	DEG_COP1_1	0.0556
p.R1918Q	DO222702	MELA	ICGC	STPGGVPSP	DEG_COP1_1	0.3056
p.T1920P	DO229491	SKCA	ICGC	STPGGVPSP	DEG_COP1_1	0.7031

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9C0A1	Zinc finger homeobox protein 2	DEG_COP1_1	1919:1927	STPGGVPSP	COP1	0.994	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons