DegronMD

Uniprot ID: Q8N7X2

Source protein: Protein STPG3

Source gene: STPG3

Class: DEG_COP1_1

Location: 98:106

E3 ligase: COP1

DEGRON score: 0.9919

ASA_SCORE: 57.2444

COIL: 0.7933

CONS_SCORE: 0.7233

DSS_SCORE: 0.5105

HELIX: 0.0352

FCONS_SCORE: 1.0217

RIG_SCORE: 0.7389

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R94C	SIDM00848	Ewing's Sarcoma	GDSC	TADLEVPSP	DEG_COP1_1	0.2222
p.R94C	A673	bone	COSMIC	TADLEVPSP	DEG_COP1_1	0.2222
p.P112R	SIDM01194	Hepatocellular Carcinoma	GDSC	TADLEVPSP	DEG_COP1_1	0.1667
p.P112R	SNU-449	liver	COSMIC	TADLEVPSP	DEG_COP1_1	0.1667
p.L101V	SIDM00568	Gastric Carcinoma	GDSC	TADLEVPSP	DEG_COP1_1	0.5654
p.L101V	OCUM-1	stomach	COSMIC	TADLEVPSP	DEG_COP1_1	0.5654

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8N7X2	Protein STPG3	DEG_COP1_1	98:106	TADLEVPSP	COP1	0.9919	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons