DegronMD

Uniprot ID: Q9H305

Source protein: Cell death-inducing p53-target protein 1

Source gene: CDIP1

Class: DEG_COP1_1

Location: 112:121

E3 ligase: COP1

DEGRON score: 0.9935

ASA_SCORE: 68.26

COIL: 0.9039

CONS_SCORE: 0.459

DSS_SCORE: 0.398

HELIX: 0.0188

FCONS_SCORE: 1.0511

RIG_SCORE: 0.7642

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.Y105F	DO46929	RECA	ICGC	TATVLVPSGA	DEG_COP1_1	0.1389
p.T124M	DO229253	THCA	ICGC	TATVLVPSGA	DEG_COP1_1	0.25
p.V124L	ACH-001560	Lung Cancer	CCLE	TATVLVPSGA	DEG_COP1_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9H305	Cell death-inducing p53-target protein 1	DEG_COP1_1	112:121	TATVLVPSGA	COP1	0.9935	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons