DegronMD - Q9H305(CDIP1)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

GO - Cellular component (CC): View more >>

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P53T	TCGA-14-0736	GBM	TCGA	PPPY	ITCH	51:54	Mutation altering degron motif	0.5919
p.P53T	DO10875	GBM	ICGC	PPPY	ITCH	51:54	Mutation altering degron motif	0.5919
p.P43S	TCGA-A5-A1OF	UCEC	TCGA	PPPY	ITCH	51:54	Mutation rewiring degron network	0.1111
p.P43S	DO42568	UCEC	ICGC	PPPY	ITCH	51:54	Mutation rewiring degron network	0.1111
p.E55D	TCGA-BT-A20R	BLCA	TCGA	PPPY	ITCH	51:54	Mutation rewiring degron network	0.3056
p.E55D	DO622	BLCA	ICGC	PPPY	ITCH	51:54	Mutation rewiring degron network	0.3056
p.E55D	DO229268	THCA	ICGC	PPPY	ITCH	51:54	Mutation rewiring degron network	0.3056
p.P46R	TCGA-E2-A1IN	BRCA	TCGA	PPPY	ITCH	51:54	Mutation rewiring degron network	0.1944
p.P46R	DO3134	BRCA	ICGC	PPPY	ITCH	51:54	Mutation rewiring degron network	0.1944
p.P7L	TCGA-ER-A42H	SKCM	TCGA	PPPY	ITCH	6:9	Mutation altering degron motif	0.7582
p.P7L	DO223909	SKCM	ICGC	PPPY	ITCH	6:9	Mutation altering degron motif	0.7582
p.E4K	DO230326	COCA	ICGC	PPPY	ITCH	6:9	Mutation rewiring degron network	0.2778
p.R30H	DO233737	GACA	ICGC	PPTPGRS	DEG_SCF_FBW7_1	25:31	Mutation altering degron motif	0.7133
p.P8S	DO27879	ORCA	ICGC	PPPY	ITCH	6:9	Mutation altering degron motif	0.5641
p.Y105F	DO46929	RECA	ICGC	TATVLVPSGA	DEG_COP1_1	112:121	Mutation rewiring degron network	0.1389
p.T124M	DO229253	THCA	ICGC	TATVLVPSGA	DEG_COP1_1	112:121	Mutation rewiring degron network	0.25
p.P10H	DO229257	THCA	ICGC	PPPY	ITCH	6:9	Mutation rewiring degron network	0.3056
p.A52V	DO223286	UCEC	ICGC	PPPY	ITCH	51:54	Mutation altering degron motif	0.6936
p.P26S	SIDM00499	Prostate Carcinoma	GDSC	PPTPGRS	DEG_SCF_FBW7_1	25:31	Mutation altering degron motif	0.5641
p.P26S	ACH-000956	Prostate Cancer	CCLE	PPTPGRS	DEG_SCF_FBW7_1	25:31	Mutation altering degron motif	0.5641
p.P26S	22RV1	prostate	COSMIC	PPTPGRS	DEG_SCF_FBW7_1	25:31	Mutation altering degron motif	0.5641
p.P46L	SIDM00216	Colorectal Carcinoma	GDSC	PPPY	ITCH	51:54	Mutation rewiring degron network	0.1944
p.P46L	SNU-175	large intestine	COSMIC	PPPY	ITCH	51:54	Mutation rewiring degron network	0.1944
p.T41I	ACH-000985	Colon/Colorectal Cancer	CCLE	PPTPGRS	DEG_SCF_FBW7_1	25:31	Mutation rewiring degron network	0.0556
p.T41I	ACH-000985	Colon/Colorectal Cancer	CCLE	PPPY	ITCH	51:54	Mutation rewiring degron network	0.0556
p.T41I	LS-411N	large intestine	COSMIC	PPTPGRS	DEG_SCF_FBW7_1	25:31	Mutation rewiring degron network	0.0556
p.T41I	LS-411N	large intestine	COSMIC	PPPY	ITCH	51:54	Mutation rewiring degron network	0.0556
p.P11L	ACH-000989	Colon/Colorectal Cancer	CCLE	PPPY	ITCH	6:9	Mutation rewiring degron network	0.2778
p.P11L	SNU-175	large intestine	COSMIC	PPPY	ITCH	6:9	Mutation rewiring degron network	0.2778
p.S37N	ACH-001203	Lymphoma	CCLE	PPTPGRS	DEG_SCF_FBW7_1	25:31	Mutation rewiring degron network	0.1667
p.S37N	SUP-HD1	haematopoietic and lymphoid tissue	COSMIC	PPTPGRS	DEG_SCF_FBW7_1	25:31	Mutation rewiring degron network	0.1667
p.V124L	ACH-001560	Lung Cancer	CCLE	TATVLVPSGA	DEG_COP1_1	112:121	Mutation rewiring degron network	0.25

Kaplan plot for CDIP1 in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CDIP1

UniProt ID: Q9H305

Entrez ID: 29965

Protein name: Cell death-inducing p53-target protein 1 (Cell death involved p53-target) (Cell death-inducing protein) (LITAF-like protein) (Lipopolysaccharide-induced tumor necrosis factor-alpha-like protein) (Transmembrane protein I1)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for CDIP1 in