DegronMD

Uniprot ID: O14523

Source protein: Phospholipid transfer protein C2CD2L

Source gene: C2CD2L

Class: LIG_APCC_ABBA_1

Location: 403:408

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.8013

ASA_SCORE: 44.0833

COIL: 0.2397

CONS_SCORE: 0.6008

DSS_SCORE: 0.5679

HELIX: 0.0112

FCONS_SCORE: 1.2444

RIG_SCORE: 0.7563

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P412H	TCGA-DZ-6132	KIRP	TCGA	VELHYE	LIG_APCC_ABBA_1	0.2222
p.Y407C	TCGA-ZF-A9R0	BLCA	TCGA	VELHYE	LIG_APCC_ABBA_1	0.5976
p.E409A	SIDM01290	Esophageal Carcinoma	GDSC	VELHYE	LIG_APCC_ABBA_1	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O14523	Phospholipid transfer protein C2CD2L	LIG_APCC_ABBA_1	403:408	VELHYE	APC,CDC20,FZR1	0.8013	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons