DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
VMSTPLLS
Uniprot ID:
Q8NET4
Source protein:
Retrotransposon Gag-like protein 9
Source gene:
RTL9
Class:
DEG_SCF_FBW7_1
Location:
319:326
E3 ligase:
FBXW7
DEGRON score:
0.5057
ASA_SCORE:
86.95
COIL:
0.827
CONS_SCORE:
0.4749
DSS_SCORE:
0.5478
HELIX:
0.0306
FCONS_SCORE:
1.1728
RIG_SCORE:
0.6841
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with RTL9 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of VMSTPLLS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8NET4
Retrotransposon Gag-like protein 9
DEG_SCF_FBW7_1
319:326
VMSTPLLS
FBXW7
0.5057
More...