DegronMD

Uniprot ID: O95822

Source protein: Malonyl-CoA decarboxylase, mitochondrial

Source gene: MLYCD

Class: DEG_SCF_FBW7_2

Location: 48:55

E3 ligase: FBXW7

DEGRON score: 0.629

ASA_SCORE: 68.0875

COIL: 0.6853

CONS_SCORE: 0.3163

DSS_SCORE: 0.5431

HELIX: 0.2681

FCONS_SCORE: 0.9061

RIG_SCORE: 0.7234

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.M40V	ACH-002348	Non-Cancerous	CCLE	VPPTPAYE	DEG_SCF_FBW7_2	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O95822	Malonyl-CoA decarboxylase, mitochondrial	DEG_SCF_FBW7_2	48:55	VPPTPAYE	FBXW7	0.629	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons