DegronMD

Uniprot ID: Q8NFC6

Source protein: Biorientation of chromosomes in cell division protein 1-like 1

Source gene: BOD1L1

Class: DEG_SCF_FBW7_1

Location: 188:194

E3 ligase: FBXW7

DEGRON score: 0.9894

ASA_SCORE: 81.8571

COIL: 0.955

CONS_SCORE: 0.5159

DSS_SCORE: 0.6169

HELIX: 0.0207

FCONS_SCORE: 0.8315

RIG_SCORE: 0.6228

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D180G	TCGA-AA-3715	COAD	TCGA	VPTPGPS	DEG_SCF_FBW7_1	0.1111
p.D180G	DO8018	COAD	ICGC	VPTPGPS	DEG_SCF_FBW7_1	0.1111
p.S203L	DO10172	COAD	ICGC	VPTPGPS	DEG_SCF_FBW7_1	0.0833
p.T185K	DO229019	LICA	ICGC	VPTPGPS	DEG_SCF_FBW7_1	0.25
p.N199S	ACH-001991	Primary	CCLE	VPTPGPS	DEG_SCF_FBW7_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8NFC6	Biorientation of chromosomes in cell division protein 1-like 1	DEG_SCF_FBW7_1	188:194	VPTPGPS	FBXW7	0.9894	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons