DegronMD

Uniprot ID: Q53F19

Source protein: Nuclear cap-binding protein subunit 3

Source gene: NCBP3

Class: DEG_APCC_DBOX_1

Location: 52:60

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.8749

ASA_SCORE: 93.5556

COIL: 0.5951

CONS_SCORE: 0.3813

DSS_SCORE: 0.4047

HELIX: 0.337

FCONS_SCORE: 1.0007

RIG_SCORE: 0.8012

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T63M	SIDM00259	Neuroblastoma	GDSC	VRRSLKELI	DEG_APCC_DBOX_1	0.25
p.T63M	SIDM00422	Hodgkin's Lymphoma	GDSC	VRRSLKELI	DEG_APCC_DBOX_1	0.25
p.T63M	SIDM01648	Non-Cancerous	GDSC	VRRSLKELI	DEG_APCC_DBOX_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q53F19	Nuclear cap-binding protein subunit 3	DEG_APCC_DBOX_1	52:60	VRRSLKELI	APC,CDC20,FZR1	0.8749	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons