DegronMD

Uniprot ID: Q9ULG3

Source protein: Uncharacterized protein CFAP92

Source gene: CFAP92

Class: DEG_SCF_FBW7_1

Location: 302:309

E3 ligase: FBXW7

DEGRON score: 0.9823

ASA_SCORE: 80.0125

COIL: 0.764

CONS_SCORE: 0.6072

DSS_SCORE: 0.3618

HELIX: 0.059

FCONS_SCORE: 0.9518

RIG_SCORE: 0.7733

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T307S	SIDM00672	Hepatocellular Carcinoma	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005
p.T307S	SIDM00454	Rhabdomyosarcoma	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005
p.T307S	SIDM00654	Small Cell Lung Carcinoma	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005
p.T307S	SIDM00529	Breast Carcinoma	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005
p.T307S	SIDM00650	Small Cell Lung Carcinoma	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005
p.T307S	SIDM00052	Esophageal Squamous Cell Carcinoma	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005
p.T307S	SIDM00703	Non-Small Cell Lung Carcinoma	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005
p.T307S	SIDM00254	Neuroblastoma	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005
p.T307S	SIDM00032	Bladder Carcinoma	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005
p.T307S	SIDM00863	Burkitt's Lymphoma	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005
p.T307S	SIDM01681	Non-Cancerous	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005
p.T307S	SIDM00760	Small Cell Lung Carcinoma	GDSC	VSRTPTIS	DEG_SCF_FBW7_1	0.6005

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9ULG3	Uncharacterized protein CFAP92	DEG_SCF_FBW7_1	302:309	VSRTPTIS	FBXW7	0.9823	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons