DegronMD

Uniprot ID: Q13614

Source protein: Myotubularin-related protein 2

Source gene: MTMR2

Class: DEG_SCF_FBW7_1

Location: 636:641

E3 ligase: FBXW7

DEGRON score: 0.9085

ASA_SCORE: 99.3667

COIL: 0.8725

CONS_SCORE: 0.2678

DSS_SCORE: 0.745

HELIX: 0.0145

FCONS_SCORE: 0.9689

RIG_SCORE: 0.7635

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.V642I	TCGA-IA-A40X	KIRP	TCGA	VTPVQT	DEG_SCF_FBW7_1	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q13614	Myotubularin-related protein 2	DEG_SCF_FBW7_1	636:641	VTPVQT	FBXW7	0.9085	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons